Diseases

Fuch’s Dystrophy

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A common adult-onset form of corneal dystrophy with autosomal dominant inheritance. The disorder is caused by mutation in the col8a2 gene. In this disease, the endothelial cells in the cornea gradually deteriorate.

SYMPTOMS

Glare and sensitivity to light.
Eye pain.
Foggy or blurred vision.
Seeing colored halos around lights.
Difficulty seeing at night.
Poor vision upon awakening that may improve later in the day.
A feeling that something is in your eye (foreign body sensation)

CAUSES

But with fuchs' dystrophy, the endothelial cells gradually die, resulting in fluid buildup (edema) within the cornea. This causes corneal thickening and blurred vision. Fuchs' dystrophy can be inherited. The genetic basis of the disease is complex — family members can be affected to varying degrees or not at all.