Diseases

Heriditary Coproporphyria

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Hereditary coproporphyria (HCP) is a disorder of heme biosynthesis, classified as an acute hepatic porphyria. HCP is caused by a deficiency of the enzyme coproporphyrinogen oxidase, coded for by the CPOX gene, and is inherited in an autosomal dominant fashion, although homozygous individuals have been identified

SYMPTOMS

Abdominal pain,nausea, vomiting, diarrhea, tachycardia,hypertension and seizures

CAUSES

This includes the acute attacks of abdominal pain,nausea, vomiting, diarrhea, tachycardia,hypertension and seizures, as well as the cutaneous findings seen in porphyria cutanea tarda (pct), namely increased skin fragility, bullous lesions after exposure to sunlight and increased scarring.