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Diseases

Non Steroidal Anti Inflammatory Ulcers

Non-steroidal anti-inflammataory drugs (nsaids) definition. Non-steroidal anti-inflammatory drugs is a class of analgesic medication that reduces pain, fever andinflammation. ... Side effects of nsaids include stomach ulcers and kidney and platelet dysfunction.

SYMPTOMS

About 15 to 20 out of 100 people who use high doses of nsaids, such as people who have rheumatoid arthritis or osteoarthritis, develop sores in the stomach that look like ulcers when examined with endoscopy. 1 but only a small number actually develop symptoms or complications of peptic ulcer disease.

CAUSES

Nsaids can cause damage to the gastroduodenal mucosa via several mechanisms, including the topical irritant effect of these drugs on the epithelium, impairment of the barrier properties of the mucosa, suppression of gastric prostaglandin synthesis, reduction of gastric mucosal blood flow and interference 

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