Diseases

Type 3 Gaucher Disease

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Type 3 gaucher's disease or glucosylceramidase deficiency: type 3 gaucher's disease is also a very rare type of gaucher's disease. Type 3 gaucher's disease begins either in childhood or in adolescence. Type 3 gaucher's disease usually results in enlargement of spleen and liver. Mild involvement of brain is also seen in type 3 gaucher's disease. Type 3 is more chronic of all the types.

SYMPTOMS

Loss of muscle coordination.
Brain problems like dementia and mental retardation.
Abnormal eye movements.

CAUSES

Gaucher's disease is usually caused due to the deficiency of enzyme glucocerebrosidase. Enzyme glucocerebrosidase helps in breaking down the fatty material known as glucocerebrosides. Gaucher's disease is an inherited disease, which passes on to the child if both the parents are carrier of gaucher's gene. In case of both the parents being carriers of the gaucher's gene, there are only 25 percent chances in a child to develop gaucher's disease.