Diseases

X Linked Leigh’s Disease

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X linked leigh’s disease is a severe neurological disorder that usually becomes apparent in the first year of life. This condition is characterized by progressive loss of mental and movement abilities (psychomotor regression) and typically results in death within two to three years, usually due to respiratory failure.

SYMPTOMS

These symptoms may be accompanied by loss of appetite, vomiting, irritability, continuous crying, and seizures. As the disorder progresses, symptoms may also include generalized weakness, lack of muscle tone, and episodes of lactic acidosis, which can lead to impairment of respiratory and kidney function.

CAUSES

Leigh's disease is caused by a defect in the function of mitochondria within the cells of the body. Symptoms begin In infancy and include poor sucking ability, the loss of head control and motor skills, loss of appetite, vomiting, irritability, continuous crying, and seizures.