Diseases
Loeys-Dietz Syndrome
An inherited syndrome characterized by aortic aneurysms and other blood vessel abnormalities in children. The condition is often associated with other birth defects. The aortic aneurysms of loeys-dietz syndrome are prone to rupture at a smaller size than other aneurysms, with early identification of the condition and surgical intervention critical for survival.
SYMPTOMS
- Translucent skin
- Soft or velvety skin
- Easy bruising
- Flat cheek bones
- Slight downward slant to the eyes
- An aneurysm, a bulge in the blood vessel wall
- Aortic dissection, sudden tearing of the layers in the aorta wall
- Long fingers and toes
- Contractures of the fingers
CAUSES
Loeys-dietz syndrome is a genetic disorder caused by a genetic mutation (error) in one of five genes.
- Tgfbr1
- Tgfbr2
- Smad-3
- Tgfbr2
- Tgfbr3
Chitradurga
Seebara, Behind Indian Oil Petrol Bunk, Basavakumara Swamy Mutt, Chitradurga - 577504
Kunigal
K Huraliborsandra, Gowdgere Post, Dhomratti Temple Road, Kunigal, Tumakuru District. - 572130
Bengaluru
36, KG Gollarapalya, Bolare (P), Kanakapura Road, Bengaluru - 560082