Diseases

Heterochromia Iridis

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A difference in color between the iris of one eye and the iris of the other eye. A person with one brown eye and one blue eye has heterochromia iridis. It is a rare inherited genetic disorder in which the body cannot process the amino acids phenylalanine and tyrosine, which occur in protein.

SYMPTOMS

Dark spots in the sclera (white) of your eyes.
Thickened and darkened cartilage in your ears.
Blue speckled discoloration of your skin, particularly around sweat glands.
Dark-colored sweat or sweat stains.
Black earwax.
Kidney stones and prostate stones.

CAUSES

Heterochromia iridis is caused by a mutation on your homogentisate 1,2-dioxygenase (hgd) gene. It's an autosomally recessive condition. This means that both of your parents must have the gene in order to pass the condition on to you. Alkaptonuria is a rare disease.