A major component and an essential ingredient of normal bone and teeth. Hydroxyapatite makes up bone mineral and the matrix of teeth. ... The inflammation caused by hydroxyapatite crystals has been referred to as hydroxyapatite crystal disease.
Acute calcific periarthritis presents with sudden onset of severe pain, swelling, tenderness, and restricted motion, with overlying redness and warmth.
Tiny crystals of hydroxyapatite sometimes form in or around joints and can cause inflammation of joints and tissues around the joints, such as tendons and ligaments. They have been described particularly as a cause of rotator cuff inflammation of the shoulder.